檢測(cè)藥物濫用準(zhǔn)確率高試紙

廣州健侖生物科技有限公司

我司同時(shí)有bzo - bar - coc - thc met - - opi - oxy - mdma - cfp - amp - xtc – bat多聯(lián)檢測(cè)卡（膠體金法）

Features

1. Accuray refer to the international drug abuse monitoring standards, designed to meet the detection threshold of the domestic situation;
2. Specific selection of highly specific monoclonal antibodies, the cross-reaction may occur to a minimum;
3. Quick urine drip 5 minutes, the naked eye can interpret the results;
4. Stability of the United States nano gold high-tech achievements, the quality of more stable than other similar products;
5. Easy to allow any equipment and additional testing, easy to operate.

檢測(cè)藥物濫用準(zhǔn)確率高試紙

Features

1. Accuray refer to the international drug abuse monitoring standards, designed to meet the detection threshold of the domestic situation;
2. Specific selection of highly specific monoclonal antibodies, the cross-reaction may occur to a minimum;
3. Quick urine drip 5 minutes, the naked eye can interpret the results;
4. Stability of the United States nano gold high-tech achievements, the quality of more stable than other similar products;
5. Easy to allow any equipment and additional testing, easy to operate.

Detection principle

For detoxification, hospitals, military conscription, census of high-risk groups, screening of special industries and recruitment of medical examination and health and epidemic prevention departments for food inspection
Use range

1, drug treatment centers, hospitals, military conscription, census of high-risk groups, special industries and hiring physical examination screening.
2, drug control agencies at the grass-roots drug screening, re-examination.
3, the grassroots police directly determine the suspicious things.
4, health and epidemic prevention department food inspection, blood stations.
5, the relevant departments for drug identification.

【Testing method】
1, read the instructions before testing;
2, take a clean urine cup urine samples (if the kit and urine samples stored in the refrigerator, please return to room temperature 18 ℃ -25 ℃);
3, Remove the test card from the aluminum foil bag, placed on a clean and flat table, with a pipette to absorb some urine samples, add 2-3 drops of sample to the sample hole perpendicular to the sample hole.
4,3-5 minutes to read the results. To ensure the accuracy of the results, do not interpret the results after 5 minutes.

[Interpretation of test results]
1, positive (drug addiction): Only one red quality control line appears in the reaction zone.
2, negative (no drug): in the reaction zone quality control line and reaction line two red lines.
3, invalid: quality control line does not appear in the reaction zone, to be re-tested.

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細(xì)菌利用IV型分泌系統(tǒng)（type IV secretion systems，T4SS）能夠轉(zhuǎn)運(yùn)毒力因子到真核細(xì)胞（如肺炎軍團(tuán)菌）、在細(xì)菌之間傳遞遺傳物質(zhì)，包括抗生素抗性基因在不同細(xì)菌之間的傳遞，促進(jìn)耐藥菌的蔓延。T4SS還可能作為對(duì)人體細(xì)胞進(jìn)行遺傳修飾的潛在工具。
2014年3月發(fā)表在Nature上的一項(xiàng)研究，揭示了細(xì)菌IV型分泌的結(jié)構(gòu)和作用機(jī)制。科研人員利用電子顯微鏡重構(gòu)了大腸桿菌R388接合型質(zhì)粒（conjugative plasmid）編碼的IV型分泌系統(tǒng)。結(jié)果表明，細(xì)菌T4SS無(wú)論是分子結(jié)構(gòu)，還是分泌機(jī)制，與其它細(xì)菌分泌系統(tǒng)都具有本質(zhì)區(qū)別。細(xì)菌IV型分泌系統(tǒng)是由8種蛋白質(zhì)組裝成的一個(gè)復(fù)雜結(jié)構(gòu)，這個(gè)結(jié)構(gòu)約3MDa，貫穿整個(gè)細(xì)菌膜。T4SS包括兩個(gè)獨(dú)立的復(fù)合體，一個(gè)位于細(xì)菌的外膜，另一個(gè)位于細(xì)菌的內(nèi)膜。它們通過(guò)一個(gè)莖狀結(jié)構(gòu)穿過(guò)胞周質(zhì)連接起來(lái)。胞周質(zhì)是位于細(xì)菌內(nèi)膜與外膜之間的空間。如此一來(lái)，在細(xì)胞膜上形成了一個(gè)孔狀結(jié)構(gòu)，細(xì)菌通過(guò)這種結(jié)構(gòu)分泌物質(zhì)。
闡明細(xì)菌IV型分泌系統(tǒng)的結(jié)構(gòu)，可以幫助人們?cè)O(shè)計(jì)新的藥物來(lái)靶向性關(guān)閉這個(gè)系統(tǒng)，從而阻止抗生素耐藥基因在細(xì)菌之間傳播。考慮到當(dāng)前細(xì)菌耐藥性已變得如此普遍，嚴(yán)重威脅著人類健康，這項(xiàng)研究結(jié)果將對(duì)未來(lái)細(xì)菌耐藥性的研究領(lǐng)域產(chǎn)生巨大的影響。巨型DNA細(xì)菌毒在光學(xué)顯微鏡下可見，它們的基因組編碼的蛋白質(zhì)比一些細(xì)菌或細(xì)胞內(nèi)寄生的真核生物還多。目前已發(fā)現(xiàn)兩種截然不同的巨型細(xì)菌毒，他們都能感染單細(xì)胞原生生物，如阿米巴原蟲（Acanthamoeba）。一方面，巨型細(xì)菌毒（Megaviridae）具有大的偽二十面體（pseudoicosahedral）衣殼包圍著大小以兆為單位、富含腺嘌呤和胸腺嘧啶的基因組；另一方面，zui近發(fā)現(xiàn)的潘多拉細(xì)菌毒（Pandoraviruses）具有微米級(jí)的雙耳罐狀顆粒和細(xì)菌達(dá)2.8 MB富含鳥嘌呤和胞嘧啶的基因組。

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【公司名稱】 廣州健侖生物科技有限公司

【 市場(chǎng)部 】       楊永漢
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【騰訊  】
【公司地址】 廣州市清華科技園健新基地番禺石樓鎮(zhèn)健啟路63號(hào)二期2幢101-103室

Bacteria use the type IV secretion systems (T4SS) to transport virulence factors into eukaryotic cells (such as Legionella pneumophila), passing on genetic material between bacteria, including the transmission of antibiotic resistance genes between different bacteria , To promote the spread of resistant bacteria. T4SS may also serve as a potential tool for genetic modification of human cells.
A study published in Nature in March 2014 revealed the structure and mechanism of bacterial type IV secretion. Researchers used electron microscopy to reconstitute a type IV secretion system encoded by the conjugate plasmid of E. coli R388. The results showed that bacterial T4SS, whether it is molecular structure or secretion mechanism, has the essential difference from other bacterial secretion systems. The bacterial type IV secretion system is a complex structure assembled from eight proteins that are about 3 Da in size throughout the bacterial membrane. T4SS consists of two separate complexes, one on the bacterial outer membrane and the other on the bacterial inner membrane. They connect through the periplasm through a stemlike structure. The periplasm is located in the space between the bacterial endometrium and the outer membrane. As a result, a cell-like structure is formed in the cell membrane by which bacteria release the substance.
Clarifying the structure of the bacterial type IV secretion system can help people design new drugs to target this system shut down and thus prevent the spread of antibiotic resistance genes among bacteria. Given the current prevalence of bacterial resistance has become so widespread that it is a serious threat to human health, the results of this study will have a huge impact on the future of bacterial resistance research. Giant DNA bacterial toxins are visible under light microscopy, and their genome encodes more proteins than some bacteria or intracellular parasitic eukaryotes. Two distinct bacterial strains of bacteria have now been discovered, all of which are capable of infecting unicellular protists, such as Acanthamoeba. On the one hand, Megaviridae has a large pseudoicosahedral capsid which encloses genomes of adenine and thymine rich in megapores; on the other hand, the recently discovered Pandora bacteria toxin Pandoraviruses) have micron-sized binocular cans and bacteria up to 2.8 MB of guanine and cytosine-rich genomes.